|
Symbol Name ID |
Ada
adenosine deaminase MGI:87916 |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased circulating IgA level |
Increased circulating IgE level |
Decreased circulating IgG2 level |
Decreased circulating total IgM |
Absent specific antibody response |
Autoimmune hemolytic anemia |
Eosinophilia |
B lymphocytopenia |
Severe B lymphocytopenia |
Lymphopenia |
Autoimmune thrombocytopenia |
Sinusitis |
Aplasia of the thymus |
Splenomegaly |
Inflammatory abnormality of the skin |
Chronic mucocutaneous candidiasis |
Skin rash |
Pneumonia |
Recurrent pneumonia |
Severe combined immunodeficiency |
Asthma |
Recurrent bacterial infections |
Recurrent fungal infections |
Recurrent viral infections |
| Disease(s) Associated with ADA | ||||||||||||||||||||||||
| adenosine deaminase deficiency | ||||||||||||||||||||||||
| asthma |
| Mouse Phenotypes | abnormal thymus corticomedullary boundary morphology |
small thymus |
increased double-negative T cell number |
decreased double-positive T cell number |
increased eosinophil cell number |
increased granulocyte number |
increased dendritic cell number |
decreased T cell number |
increased macrophage cell number |
decreased leukocyte cell number |
abnormal spleen red pulp morphology |
small spleen |
spleen hypoplasia |
decreased immunoglobulin level |
abnormal dendritic cell physiology |
lung inflammation |
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| Availability | Mouse Genotype | ||||||||||||||||
| Adatm1Mw/Adatm1Mw | |||||||||||||||||
| Adatm1Mw/Adatm1Mw Tg(PLADA)4118Rkmb/0 |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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